Research in our group is interdisciplinary and focuses on the design and fabrication of biosensors and chemical sensors. We seek to understand how surfaces and biointerfaces, biological and chemical functionalization, and fabrication parameters translate into heightened performance in sensors and biosensors. The sensors we investigate are both optical/colorimetrical and electrochemical. We also have a focus area in electrochemistry as related to batteries. Use the menu above to learn more.

 
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Aptamer whole-cell detection of pathogens, detection of toxins and disease markers

Aptamers are DNA fragments that have the ability to bind to a large array of targets. Exploring the use of aptamers in biosensensing is one focus of our laboratory.

Aptamers maintain the specificity of antibodies, at a fraction of the cost. Moreover, aptamers are much more stable under harsh environmental conditions compared to aptamers, making them especially suitable for being implemented into mass fabrication processes.

 

roll-to-roll fabrication of sensors and biosensors

Although there are tens of thousands of research articles focusing on biosensors being published yearly, very few of these devices meet the market.

In our group, we work on overcoming the challenges that stand in the way of biosensor commercialization. This includes inkjet printing of biological elements on paper based devices and roll-to-roll fabrication of electrochemical sensors.

Our group put forward:

  1. The first aptamer-based whole cell lateral flow assay

  2. The first ink-jet bio-patterning of aptameric inks

  3. Statistical analysis based on image analysis of colorimetric test strips (signal quantification)

  4. Novel carboxyl-DNA modification of aptamers

  5. In progress: SELEX process to fabricate aptamers in our own laboratory

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